Introduction
My research is focussed on unraveling the orchestration of membrane-proximal phosphotyrosine signalling events by studying the phosphotyrosine-altering genetic variants linked to human disease-related traits. By combining synthetic biology and animal models of cancers I uncover the molecular basis of genetically determined differences in the progression and prognosis of complex human diseases such as autoimmunity and cancer.
2010 : PhD (Autoimmunity) LMU Munich/Max Planck Institute of Neurobiology, Germany
2010-2011 : Post-doc (Kinase Signaling in Cancer Progression) Max Planck Institute of Biochemistry, Germany
2012-2018 : Project Leader (Genetic variants of tyrosine phosphorylation) Max Planck Institute of Biochemistry, Germany
2018-2021 : Research Group Leader (Phosphotyrosine-altering genetic variants in immune signaling pathways) Universitätsmedizin Göttingen, Germany
- Teaching
- Research Project Supervision
- M2 Internships, Third party funding acquisition, Reserach projects co-ordination
Investigating the molecular basis of the association of phosphotyrosine-altering genetic variants with complex human disease-related traits
B.Pharm (Pharmacy), The Tamil Nadu Dr. M.G.R Medical University, Chennai, India
M.Tech (Biological Sciences & Bioengineering), IIT Kanpur, India
M2 Thesis-1 : A computations tool to quantify genome-encoded tyrosine phosphorylation sites
M2 Thesis-2 : Uncovering the role of STAT3-enhancing receptor variants in cell metabolism