Le Professeur Jean-Louis Guéant, directeur du Laboratoire NGERE UMRS INSERM 1256 organise avec la FASEB et le soutien de Lorraine Université d’Excellence une Autumn School 100% en ligne et en anglais, qui se tiendra du 18 au 20 octobre 2021 :
« The Epigenome in Human Health and Diseases Conference »
The Epigenome in Human Health and Diseases Conference
MONDAY, OCTOBER 18, 2021
| US Eastern Daylight Time (EDT) / Central European Summer Time (CEST) | Event |
|---|---|
| 8:30 am – 8:45 am (EDT) / 2:30 pm – 2:45 pm (CEST) | Opening Remarks Pierre Mutzenhardt, President of the University of Lorraine, France |
| 8:45 am – 9:00 am (EDT) / 2:45 pm – 3:00 pm (CEST) | Introduction of the Autumn School Jean-Louis Guéant, University of Lorraine, France |
| Day 1 Topic: Basics Aspects | |
| 9:00 am – 12:00 pm (EDT) / 3:00 pm – 6:00 pm (CEST) | Morning Session Session Chair: Germano Cecere (Institut Pasteur, France) |
| 9:00 am – 10:00 am (EDT) / 3:00 pm – 4:00 pm | John Edwards (Center for Pharmacogenomics, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA) “DNA Methylation and DNA Methyltransferases” (45 min presentation, 10 min Q&A, 5 min break) |
| 10:00 am – 11:00 pm (EDT) / 4:00 pm – 5:00 pm | Jordana Bell (King’s College London, UK) “Genetic Impacts on DNA Methylation” (45 min presentation, 10 min Q&A, 5 min break) |
| 11:00 am – 12:00 pm (EDT) / 5:00 pm – 6:00 pm | Eric Verdin (Buck Institute for Research on Aging, Novato, CA, USA) “Chromatin Regulation and Intermediary Metabolism” (45 min presentation, 10 min Q&A, 5 min break) |
| 12:00 pm – 1:00 pm (EDT) / 6:00 pm – 7:00 pm (CEST) | Lunch Break |
| 1:00 pm – 2:00 pm (EDT) / 7:00 pm – 8:00 pm (CEST) | Poster Session Poster Presenters with last name beginning with A-L will need to stay in their Poster Chat Room to answer questions from attendees |
| 2:00 pm – 4:00 pm (EDT) / 8:00 pm – 10:00 pm (CEST) | Afternoon Session Session Chair: Guillermo Barreto (University of Lorraine, France) |
| 2:00 pm – 3:00 pm (EDT) / 8:00 pm – 9:00 pm | Jean-Yves Roignant (Faculté de Biologie et de Médecine, Université de Lausanne, Switzerland) “RNA Methylation” (45 min presentation, 10 min Q&A, 5 min break) |
| 3:00 pm – 4:00 pm (EDT) / 9:00 pm – 10:00 pm | Germano Cecere (Institut Pasteur, France) “RNA Mechanisms of Epigenetic Inheritance” (45 min presentation, 10 min Q&A, 5 min break) |
| 4:00 pm – 4:30 pm (EDT) / 10:00 pm – 10:30 pm (CEST) | Break |
| 4:30 pm – 5:30 pm (EDT) / 10:30 pm – 11:30 pm (CEST) | Round table with the speakers of the day – Presentation and discussion of selected projects related to the topics of the day Session Co-Chairs: Jordana Bell (King’s College London, UK) and Jonathan Turner (Luxembourg Institute of Health, Luxembourg) Xiaopu Zhang (King’s College, London) « Identification of Genetic Impacts on Human DNA Methylation Variability » (12 min presentation, 8 min discussion) Pauline Mosca (University of Lorraine, France) « Vitamin B 12 Deficiency Dysregulates m6A mRNA Methylation of Genes Involved in Neurological Functions » (12 min presentation, 8 min discussion) Hong Nhung Vu (Université de Iceland, Iceland) « Functional Role of PRDM7 in Melanoma and Its Regulation by MITF » (12 min presentation, 8 min discussion) |
Tuesday, October 19, 2021
| US Eastern Daylight Time (EDT) / Central European Summer Time (CEST) | Event |
|---|---|
| Day 2 Topic: The epigenome and environmental exposure in populations | |
| 9:00 am – 12:00 pm (EDT) / 3:00 pm – 6:00 pm (CEST) | Morning Session Session Chair: Janine Felix (Erasmus MC, Department of Pediatrics, Rotterdam, The Netherlands) |
| 9:00 am – 10:00 am (EDT) / 3:00 pm – 4:00 pm (CEST) | Abderrahim Oussalah (Inserm UMRS 1256 N-GERE, Nutrition-Genetics-Environmental Risks, University of Lorraine, France) “Bioinformatics Approaches in EWAS” (45 min presentation, 10 min Q&A, 5 min break) |
| 10:00 am – 11:00 pm (EDT) / 4:00 pm – 5:00 pm (CEST) | Guillaume Bourque (McGill University & Genome Quebec Innovation Center, Montreal, Canada) “Data Repository-based Approaches in Comparative and Functional Epigenomics” (45 min presentation, 10 min Q&A, 5 min break) |
| 11:00 am – 11:30 pm (EDT) / 5:00 pm – 5:30 pm (CEST) | Patrick Anglard (CNRS and University of Strasbourg, France) « Epigenetic Regulation of Circadian Clocks and Its Involvement in Drug Addiction » (25 min presentation, 5 min Q&A) |
| 11:30 am – 12:00 pm (EDT) / 5:30 pm – 6:00 pm (CEST) | Jonathan Turner (Luxembourg Institute of Health, Luxembourg) « Moving Away from 5-methyl-Cytosine: The Role of 6mA in Our Adaptation to the Early Life Environment » (25 min presentation, 5 min Q&A) |
| 12:00 pm – 1:00 pm (EDT) / 6:00 pm – 7:00 pm (CEST) | Lunch Break |
| 1:00 pm – 2:00 pm (EDT) / 7:00 pm – 8:00 pm (CEST) | Poster Session Poster Presenters with last name beginning with M-Z will need to stay in their Poster Chat Room to answer questions from attendees |
| 2:00 pm – 4:00 pm (EDT) / 8:00 pm – 10:00 pm (CEST) | Afternoon Session Session Chair: Guillaume Bourque (McGill University & Genome Quebec Innovation Center, Montreal, Canada) |
| 2:00 pm – 3:00 pm (EDT) / 8:00 pm – 9:00 pm (CEST) | Janine Felix (Erasmus MC, Department of Pediatrics, Rotterdam, The Netherlands) “Pregnancy Exposures, Offspring DNA Methylation and Later-Life Health” (45 min presentation, 10 min Q&A, 5 min break) |
| 3:00 pm – 4:00 pm (EDT) / 9:00 pm – 10:00 pm (CEST) | Philippa Melamed (Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel) “Epigenetic Mechanisms Regulating Reproduction and the Early-Life Environment” (45 min presentation, 10 min Q&A, 5 min break) |
| 4:00 pm – 4:30 pm (EDT) / 10:00 pm – 10:30 pm (CEST) | Break |
| 4:30 pm – 5:30 pm (EDT) / 10:30 pm – 11:30 pm (CEST) | Round table with the speakers of the day – Presentation and discussion of selected projects related to the topics of the day Session Co-Chairs: Abderrahim Oussalah (University of Lorraine, France), David Meyre (University of Lorraine, France) Cyrielle Holucka (Luxembourg Institute of Health, Luxembourg) « Early Life Adversity Accelerates the Aging Process » (12 min presentation, 8 min discussion) Youssef Siblini (NGERE, University of Lorraine, France) « Ionizing Radiations Induce Shared Epigenomic Signatures Unraveling Adaptive Mechanisms of Cancerous Cell Lines With or Without Methionine-Dependency » (12 min presentation, 8 min discussion) Alexandre Pelletier (Université de Lille, France) « Excessive Fetal Growth Affects HSC Homeostasis through Epigenetic Programming of the EGR1 Associated Transcriptional Network » (12 min presentation, 8 min discussion) |
Wednesday, October 20, 2021
| US Eastern Daylight Time (EDT) / Central European Summer Time (CEST) | Event |
|---|---|
| Day 3 Topic: Epigenome and Diseases | |
| 9:00 am – 12:00 pm (EDT) / 3:00 pm – 6:00 pm (CEST) | Morning Session Session Chair: Struan Grant (Center for Spatial and Functional Genomics, Divisions of Human Genetics and Endocrinology & Diabetes, Children’s Hospital of Philadelphia, PA, USA) |
| 9:00 am – 10:00 am (EDT) / 3:00 pm – 4:00 pm (CEST) | Struan Grant (Center for Spatial and Functional Genomics, Divisions of Human Genetics and Endocrinology & Diabetes, Children’s Hospital of Philadelphia, PA, USA) “Epigenome and Obesity-related Diseases” (45 min presentation, 10 min Q&A, 5 min break) |
| 10:00 am – 11:00 pm (EDT) / 4:00 pm – 5:00 pm (CEST) | Manel Esteller (Josep Carreras Leukaemia Research Institute (IJC), Badalona, Barcelona, Spain) « Epigenome in Cancer » (45 min presentation, 10 min Q&A, 5 min break) |
| 11:00 am – 12:00 pm (EDT) / 5:00 pm – 6:00 pm (CEST) | Esteban Ballestar (Epigenetics and Immune Disease Group, Josep Carreras Research Institute (IJC), Badalona, Barcelona, Spain) « Epigenetics in Immune Diseases and Disorders » (45 min presentation, 10 min Q&A, 5 min break) |
| 12:00 pm – 1:00 pm (EDT) / 6:00 pm – 7:00 pm (CEST) | Lunch Break |
| 1:00 pm – 2:00 pm (EDT) / 7:00 pm – 8:00 pm (CEST) | Poster Session Free Discussion |
| 2:00 pm – 4:00 pm (EDT) / 8:00 pm – 10:00 pm (CEST) | Afternoon Session Session Chair: Jean-Louis Guéant (University of Lorraine, France) |
| 2:00 pm – 2:30 pm (EDT) / 8:00 pm – 8:30 pm (CEST) | Rosa-Maria Guéant-Rodriguez (Inserm UMRS 1256 N-GERE (Nutrition-Genetics-Environmental Risks), University of Lorraine, France) « The Epigenome in Cardiovascular Diseases » (25 min presentation, 5 min Q&A) |
| 2:30 pm – 3:00 pm (EDT) / 8:30 pm – 9:00 pm (CEST) | Guillermo Barreto (University of Lorraine, France) « Epigenetic Regulation of Transcription and Spatial Genome Organization during Chronic Lung Diseases » (25 min presentation, 5 min Q&A) |
| 3:00 pm – 4:00 pm (EDT) / 9:00 pm – 10:00 pm (CEST) | Jean-Louis Guéant (Inserm UMRS 1256 N-GERE (Nutrition-Genetics-Environmental Risks), University of Lorraine, France) “Epigenome and Rare Diseases” (45 min presentation, 10 min Q&A, 5 min break) |
| 4:00 pm – 4:30 pm (EDT) / 10:00 pm – 10:30 pm (CEST) | Break |
| 4:30 pm – 5:30 pm (EDT) / 10:30 pm – 11:30 pm (CEST) | Round table with the speakers of the day – Presentation and discussion of selected projects related to the topics of the day Session Co-Chairs: Struan Grant (Children’s Hospital of Philadelphia, PA, USA) and Esteban Ballestar (Josep Carreras Leukaemia Research Institute (IJC), Badalona, Barcelona) María Silvia Román Azcona (Albert-Ludwigs Universität Freiburg, Germany) « Epigenome Editing Enables PD1 Silencing in Primary T-cells » (12 min presentation, 8 min discussion) Sofia Raquel Fernandes Salta (Université de Porto, Portugal) « Triage of hr-HPV Positive Women Enrolled in Cervical Cancer Screening Program: DNA Methylation Markers as Potential Tool » (12 min presentation, 8 min discussion) Ramia Safar (NGERE, University of Lorraine, France) « Epigenome Alterations in Food Allergy: A Systematic Review of Candidate Gene and Epigenome-Wide Association Studies » (12 min presentation, 8 min discussion) |
| 5:30 pm – 6:00 pm (EDT) / 11:30 pm – 12:00 am (CEST) |
| Concluding Discussion |
